Name: KPV 5mg (10 Vials / Kit)
Brand: HK Peptide
SKU: HK-KPV5
Price: 35.00 USD
Availability: InStock

What is KPV?

KPV (Lys-Pro-Val) corresponds to residues 11-13 of alpha-melanocyte-stimulating hormone, the smallest fragment reported to retain meaningful biological activity from the parent peptide. Because it lacks the sequence responsible for melanocortin receptor-driven pigmentation, researchers use it to isolate alpha-MSH’s anti-inflammatory effects from its pigment-related actions.

How it is understood to work

KPV is studied for its ability to enter cells via the PepT1 peptide transporter, which is highly expressed in intestinal and skin tissue, and to inhibit NF-kB signaling once inside, reducing production of pro-inflammatory cytokines. Some in vitro work also describes direct antimicrobial activity against certain bacterial strains.

Research status

The tripeptide has been examined mainly in cell culture and rodent models of colitis, inflammatory bowel conditions, dermatitis and wound healing; it has not been evaluated in registered human clinical trials, and its transporter-dependent uptake means results can vary meaningfully between tissue types used in different study models.

This listing: HK Peptide KPV

Brand: HK Peptide
Kit: 10 vials × 5 mg (50 mg in total)
Price per vial: $3.50
Price per mg: $0.70
Other strengths: 10mg $55.00
Also sold by: Uther Peptide 10mg $80.00 · Uther Peptide 30mg $150.00

Lab testing

HK Peptide published a Janoshik #121855 report for this compound. Test: Purity & Content (HPLC). Result: 99.23% purity · 12.88 mg. Tested Mar 16, 2026. The vial tested was a different strength than this listing, so treat it as evidence for the compound and ask for the batch COA for this exact strength. Verification key 5VZXZD8NAF97 can be checked at janoshik.com.

View the report · How to read it (Testing 101) · Every report for this compound

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

Specifications

Compound: KPV
Also known as: Lys-Pro-Val, alpha-MSH(11-13)
Class: Naturally occurring tripeptide, C-terminal alpha-MSH fragment
Form: Lyophilized (freeze-dried) powder
Per vial: 5mg
Molecular formula: C₁₆H₃₀N₄O₄
Molecular weight: 342.4 g/mol
Sequence: Lys-Pro-Val
Stated purity: ≥99% (HPLC)
Appearance: White lyophilized powder

Handling & storage

Supplied as a lyophilized powder; store unopened vials at -20C protected from light, and once reconstituted with bacteriostatic water keep refrigerated at 2-8C for use within the study’s defined timeframe.

Concentration check: adding 2 ml of bacteriostatic water to one 5 mg vial gives 2.5 mg/ml. The Research Lab calculator in your dashboard works this out for any volume.

Questions

How does KPV differ from full-length alpha-MSH?

KPV retains only the three C-terminal residues of alpha-MSH and lacks the N-terminal sequence responsible for melanocortin receptor binding and pigmentation, so research models use it to study anti-inflammatory activity separately from pigment-related signaling.

What should a COA confirm for KPV?

Sequence identity (Lys-Pro-Val), molecular weight near 342 g/mol, and HPLC purity of 99% or higher, ideally from an independent lab given how short and easily miscategorized tripeptides can be on lower-resolution testing.

How much KPV is in this kit?

10 vials of 5 mg each, so 50 mg in total. The lab testing section above shows what the brand’s tested vial actually contained.

For laboratory research use only. Not for human or veterinary use. Nothing on this page is medical advice.