Semax

What is Semax?

Semax is built from the ACTH(4-7) fragment of adrenocorticotropic hormone, extended with a Pro-Gly-Pro sequence that improves metabolic stability. Despite its ACTH lineage, it does not retain the hormone’s corticotropic (adrenal-stimulating) activity.

This listing is Semax from Vital Edge Science (Australia & New Zealand), sold on Stairway to Gray with escrow: your payment is held until the order arrives and only then released to the brand.

How it is understood to work

Semax is studied for its ability to increase expression of brain-derived neurotrophic factor (BDNF) and its TrkB receptor, along with modulation of dopaminergic and serotonergic signaling and antioxidant activity in models of reduced blood flow to brain tissue.

Research status

It is approved and marketed as a nasal-spray medicine in Russia for conditions including stroke recovery and certain cognitive complaints, though it has not received FDA or EMA approval and is not an approved medicine in the US or EU. Outside that regulatory context, it is studied preclinically for cognition, memory, attention and neuroprotection.

Specifications

Compound

Semax

Also known as

ACTH(4-10) analog

Class

Synthetic ACTH-fragment neuropeptide

Form

Lyophilized (freeze-dried) powder

Brand

Vital Edge Science · Australia & New Zealand

Handling & storage

Supplied as a lyophilized powder; store unopened vials at -20 C protected from light, and after reconstitution with bacteriostatic water keep refrigerated and use within the timeframe set by the study protocol.

Questions

For laboratory research use only. Not for human or veterinary use. Nothing on this page is medical advice.