Name: IGF-1 LR3 1mg (10 Vials / Kit)
Brand: SynTide Research
SKU: ST-IGF1LR3
Price: 35.00 USD
Availability: InStock

What is IGF-1 LR3?

IGF-1 LR3 modifies native human IGF-1 by substituting arginine for glutamic acid at position 3 and adding a 13-residue extension at the N-terminus. These changes were designed specifically to reduce its affinity for the binding proteins that normally regulate native IGF-1 activity.

This listing is IGF-1 LR3 (10 vials × 1mg) from SynTide Research (China), sold on Stairway to Gray with escrow: your payment is held until the order arrives and only then released to the brand.

How it is understood to work

By evading binding proteins, IGF-1 LR3 remains active in solution far longer than native IGF-1, activating the IGF-1 receptor to drive PI3K/Akt and MAPK signaling cascades associated with cell proliferation, differentiation and protein synthesis.

Research status

It is a standard tool in cell-culture research, particularly studies of muscle satellite-cell proliferation, hypertrophy signaling and general growth-factor biology, where its extended activity window makes it useful compared with native IGF-1. It has not been developed as an approved therapeutic and clinical safety data in humans is limited.

This listing: SynTide Research IGF-1 LR3

Brand: SynTide Research
Kit: 10 vials × 1 mg (10 mg in total)
Price per vial: $3.50
Price per mg: $3.50
Also sold by: Jinlu Peptides 1mg $225.00 · European Peptide Sciences 1mg $599.00 · SSRBIO 1mg $158.22 · Lianhua Peptide Co. 1mg $68.00 · Sulan Bio 1mg $190.00 · TFC Peptides 1mg $180.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

Specifications

Compound: IGF-1 LR3
Also known as: Long R3 IGF-1
Class: Long-acting insulin-like growth factor 1 analog
Form: Lyophilized (freeze-dried) powder
Per vial: 1mg
Units per kit: 10
Brand: SynTide Research · China

Handling & storage

Supplied as a lyophilized powder; store unopened vials at -20 C protected from light, and after reconstitution with bacteriostatic water keep refrigerated and use within the timeframe set by the study protocol.

Concentration check: adding 2 ml of bacteriostatic water to one 1mg vial gives 0.5 mg/ml. The Research Lab calculator in your dashboard works this out for any volume.

Questions

Why use IGF-1 LR3 instead of native IGF-1 in a study?

Native IGF-1 is rapidly bound and cleared from solution, giving it a half-life of minutes; the LR3 modification resists that binding, giving researchers a longer, more stable signaling window for in vitro work.

Does IGF-1 LR3 activate the insulin receptor as well?

At sufficiently high concentrations IGF-1 LR3 can cross-react with the insulin receptor, which is a consideration researchers account for when interpreting metabolic versus growth-signaling data in a given assay.

How much IGF-1 LR3 is in this kit?

10 vials of 1mg each. The lab testing section above shows what the brand’s tested sample actually contained, where a report exists.

For laboratory research use only. Not for human or veterinary use. Nothing on this page is medical advice.