Name: Semax 5mg
Brand: Imperial Peptides
SKU: IMP-1705
Price: 28.00 USD
Availability: InStock

What is Semax?

Semax is built from the ACTH(4-7) fragment of adrenocorticotropic hormone, extended with a Pro-Gly-Pro sequence that improves metabolic stability. Despite its ACTH lineage, it does not retain the hormone’s corticotropic (adrenal-stimulating) activity.

This listing is Semax 5mg from Imperial Peptides (Australia), sold on Stairway to Gray with escrow: your payment is held until the order arrives and only then released to the brand.

How it is understood to work

Semax is studied for its ability to increase expression of brain-derived neurotrophic factor (BDNF) and its TrkB receptor, along with modulation of dopaminergic and serotonergic signaling and antioxidant activity in models of reduced blood flow to brain tissue.

Research status

It is approved and marketed as a nasal-spray medicine in Russia for conditions including stroke recovery and certain cognitive complaints, though it has not received FDA or EMA approval and is not an approved medicine in the US or EU. Outside that regulatory context, it is studied preclinically for cognition, memory, attention and neuroprotection.

This listing: Imperial Peptides Semax

Brand: Imperial Peptides
Also sold by: TFC Peptides 5mg $35.00 · HK Peptide 5mg $40.00 · Cyprus Peptides 5mg $97.00 · Lilipeptide Semax $52.00 · Vital Edge Science Semax $45.00 · Peptide Express 10mg $40.00

Lab testing

Imperial Peptides published a Janoshik #105937 report for this compound. Test: Purity & Content (HPLC). Result: 99.75% purity · 5.52 mg. Tested Feb 10, 2026. Verification key ZRCG2MKU3MJE can be checked at janoshik.com.

View the report · How to read it (Testing 101) · Every report for this compound

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

Specifications

Compound: Semax
Also known as: ACTH(4-10) analog
Class: Synthetic ACTH-fragment neuropeptide
Form: Lyophilized (freeze-dried) powder
Per vial: 5mg
Brand: Imperial Peptides · Australia

Handling & storage

Supplied as a lyophilized powder; store unopened vials at -20 C protected from light, and after reconstitution with bacteriostatic water keep refrigerated and use within the timeframe set by the study protocol.

Concentration check: adding 2 ml of bacteriostatic water to one 5mg vial gives 2.5 mg/ml. The Research Lab calculator in your dashboard works this out for any volume.

Questions

Is Semax the same as ACTH, and does it affect cortisol?

No. Although derived from an ACTH fragment, Semax’s structural modifications remove the corticotropic activity responsible for stimulating adrenal cortisol production, which is why it is studied for CNS effects rather than endocrine ones.

Is Semax an approved medicine anywhere?

Yes, it is approved and sold as a prescription nasal spray in Russia, but it has not been approved by the FDA or EMA, so its regulatory status differs substantially between regions.

For laboratory research use only. Not for human or veterinary use. Nothing on this page is medical advice.