MOTS-C 5mg

What is MOTS-c?

MOTS-c belongs to a small class of mitochondrial-derived peptides, meaning its coding sequence lies within the mitochondrial genome rather than nuclear DNA, specifically within the 12S rRNA region. This origin sets it apart from most research peptides, which are modeled on nuclear-encoded proteins or hormones, and has made it a focus of mitochondrial-signaling research.

This listing is MOTS-c 5mg from Cyprus Peptides (Cyprus), sold on Stairway to Gray with escrow: your payment is held until the order arrives and only then released to the brand.

How it is understood to work

MOTS-c is studied for activating the AMPK energy-sensing pathway and influencing the folate-methionine metabolic cycle, effects linked in cell and animal models to improved glucose uptake and insulin sensitivity. Under metabolic stress, it has also been reported to translocate to the cell nucleus, where it may participate in regulating adaptive gene-expression programs.

Research status

Published work spans cell culture and rodent models of insulin resistance, diet-induced obesity, exercise capacity and age-related metabolic decline, framing MOTS-c as a candidate signaling molecule linking mitochondrial state to whole-body metabolism; it has not progressed to human clinical trials or approved use, and its physiological role outside laboratory models is still being defined.

Specifications

Compound

MOTS-c

Also known as

Mitochondrial ORF of the 12S rRNA-c

Class

Mitochondrial-derived peptide (16 amino acids)

Form

Lyophilized (freeze-dried) powder

Molecular formula

C₁₀₁H₁₅₂N₂₈O₂₂S₂

Molecular weight

2174.6 g/mol

Sequence

Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro

Per vial

5mg

Brand

Cyprus Peptides · Cyprus

Handling & storage

Supplied as a lyophilized powder; store unopened vials at -20C protected from light, and once reconstituted with bacteriostatic water keep refrigerated at 2-8C for use within the study’s defined timeframe.

Concentration check: adding 2 ml of bacteriostatic water to one 5mg vial gives 2.5 mg/ml. The Research Lab calculator in your dashboard works this out for any volume.

Questions

For laboratory research use only. Not for human or veterinary use. Nothing on this page is medical advice.