Name: Semaglutide
Brand: Lilipeptide
SKU: LILI-semaglutide
Availability: OutOfStock

What is Semaglutide?

Semaglutide shares about 94 percent sequence identity with native glucagon-like peptide-1, differing by two amino-acid substitutions plus a C18 fatty-diacid side chain that lets it bind circulating albumin. That albumin binding protects it from rapid DPP-4 breakdown and extends its functional half-life to roughly a week, a major departure from short-lived native GLP-1.

This listing is Semaglutide from Lilipeptide (China), sold on Stairway to Gray with escrow: your payment is held until the order arrives and only then released to the brand.

How it is understood to work

Semaglutide activates the GLP-1 receptor to stimulate glucose-dependent insulin secretion and suppress glucagon release, while also acting on hypothalamic appetite centers and slowing gastric emptying. Together these actions reduce overall energy intake in study models, and because insulin release stays glucose-dependent, the mechanism carries a comparatively low intrinsic risk of driving hypoglycemia on its own.

Research status

Semaglutide is the active ingredient in approved GLP-1 medicines, giving it an unusually deep base of both preclinical and large-scale human clinical trial data for type 2 diabetes and obesity. Newer research extends into cardiovascular risk reduction, hepatic fat, kidney outcomes and early exploration of neurodegenerative pathways, an active and still-evolving area.

This listing: Lilipeptide Semaglutide

Brand: Lilipeptide
Also sold by: Peptide Express 10mg $105.00 · HK Peptide 10mg $70.00 · TFC Peptides 10mg $60.00 · Sulan Bio 10mg $95.00 · Lianhua Peptide Co. 10mg $58.00 · SSRBIO 10mg $45.54

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

Specifications

Compound: Semaglutide
Also known as: GLP-1 receptor agonist (semaglutide)
Class: GLP-1 receptor agonist
Form: Lyophilized (freeze-dried) powder
Molecular formula: C₁₈₇H₂₉₁N₄₅O₅₉
Molecular weight: 4113.6 g/mol
Appearance: White lyophilized powder
Brand: Lilipeptide · China

Handling & storage

Supplied as a lyophilized powder; keep unopened vials frozen and protected from light, and once reconstituted with bacteriostatic water, store refrigerated and use within the timeframe set by your protocol.

Questions

Is this the same molecule as in the approved medicines?

Yes, the semaglutide sequence itself is the same active peptide used in those approved products; what differs here is that it is supplied as an unformulated research material rather than in an approved clinical dosage form and delivery device.

Why does the fatty-diacid side chain matter?

That side chain is what allows the peptide to bind serum albumin and resist rapid enzymatic breakdown, the specific modification responsible for extending semaglutide’s functional half-life from minutes, for native GLP-1, to roughly a week.

For laboratory research use only. Not for human or veterinary use. Nothing on this page is medical advice.